The Obare Method Calculator is a tool to support researchers using microscopy in malaria research by calculating the mean parasite density and assessing whether two blood samples are concordant. It is a Microsoft Excel-based tool developed to facilitate adherence to the recommendations for internal quality control (IQC) defined in the recently released methods manual ‘Microscopy for the detection, identification and quantification of malaria parasites on stained thick and thin blood films in research settings’ (WHO 2015).