Procedures

WWARN is continually updating a library of standardised procedures that offer guidance in the execution of various activities in the fields of clinical, in vitro, pharmacology, data collection and molecular analysis for antimalarial drug resistance researchers. Please read our tools and resources usage guidance.

For resources that relate to other infectious and emerging diseases, visit iddo.org.

DNA Extraction: Preparing Rapid Diagnostic Tests

Publication Code: MOL06

Storing and processing malaria Rapid Diagnostic Tests (RDTs) for DNA extraction

Version: v1.1

Author(s): WWARN

Preparation of Culture Medium

Publication Code: INV02

Preparing complete medium for Plasmodium falciparum cultures

Version: v1.1

Author(s): WWARN

Leukocyte Depletion of Whole Blood Using CF11 Columns

Publication Code: MOL02

Version: v1.3

Author(s): WWARN

Extraction and storage of genetic material

Publication Code: CL16

A general process for collecting and processing of genetic material from blood samples in clinical trials

Version: 2.0

Author(s): WWARN

Management of acute hemolysis (primaquine for P vivax)

Publication Code: CL08

An approach to managing suspected haemolysis in participants taking part in trials using primaquine for P vivax infection

Version: 1.0

Author(s): IMPROV trial group

Measuring respiratory rate

Publication Code: CL05

A process for measuring and recording respiratory rate in participants enrolled in an antimalarial drug trial

Version: 2.0

Author(s): WWARN

Measuring temperature by ThermoScan

Publication Code: CL01

A procedure for measurement/recording of tympanic membrane temperature using the Braun ThermoScan in participants enrolled in malaria drug trials

Version: 2.0

Author(s): WWARN

Management of acute haemolysis (low dose primaquine)

Publication Code: CL09

A simplified process for field site staff to identify and manage any cases of suspected acute haemolysis in a clinical trial (such as trials involving low-dose primaquine)

Version: 2.0

Author(s): WWARN

Blood PK sample processing and transport

Publication Code: CL14

A process for taking pharmacokinetic samples from the participant through an interim processing laboratory and onto an analytical laboratory

Version: 2.0

Author(s): WWARN

Late antimalarial treatment failure

Publication Code: CL07

A process for case management of patients with uncomplicated malaria who fail first line treatment in antimalarial drug field trials

Version: 1.0

Author(s): CCOAT