Study Groups
WWARN facilitates a number of collaborative Study Groups to undertake individual patient data meta-analyses to answer specific research questions about malaria treatments and antimalarial drug resistance. Gathering and combining data sets from multiple studies increases sample sizes, so that effects, including smaller effects, and effects on sub-populations can be identified with greater certainty. Working together and combining data from different regions and populations is improving our understanding of drug resistance and strengthening global efforts to control and eventually eliminate malaria.
![Dominic Chavez World Bank clinic_in_bamako](/sites/default/files/styles/standard_image_crop/public/page/clinic_in_bamako-dominic_chavezworld_bank.jpg?itok=D8rDR-D3)
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Dominic Chavez World Bank
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Analysis of how age impacts the effect of primaquine dose on gastrointestinal tolerability in patients with Plasmodium vivax and Plasmodium ovale mala...
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Development of statistical methods to infer the relationship between the percentage of resistant infections, parasite clearance half-life and the prop...
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Analysis of how age impacts the effect of primaquine dose on haematological safety in patients with Plasmodium vivax and Plasmodium ovale malaria
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The paediatric single low-dose (SLD) primaquine safety study group aims to describe and compare the safety of SLD primaquine for transmission blocking...
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Analysis of the effect of primaquine dose on tolerability and Plasmodium vivax recurrence.
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This is an extension of a planned dihydroartemisinin-piperaquine (DP) Safety Study Group, which aims to consider the effect of HIV disease and co-admi...
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An analysis of pooled individual patient data to determine the effect of antiretroviral (ARV) drug-drug interactions and HIV disease on lumefantr...
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![Photo Dominic Chavez, World Bank mothers and babies in health centre. Sierra Leone](/sites/default/files/styles/research_activity_480x270/public/2024-02/mothers%20and%20babies%20in%20health%20centre.%20Sierra%20Leone%20Photo%20Dominic%20Chavez%20World%20Bank.jpg?itok=u7MzyfqY)
This study group aims to determine the impact of malaria in the first trimester of pregnancy on the mother and infant through individual patient data ...
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Pooled analyses of the efficacy and safety of single low-dose primaquine to interrupt P. falciparum malaria transmission.Data collection has closed an...
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This Study Group will explore the link between P. vivax recurrence and prior P. falciparum treatment, including increased risk of vivax para...
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![Pregnant woman sitting against a wall](/sites/default/files/styles/research_activity_480x270/public/migrated/images/study-groups/pregnant_woman-credit-doune_porter-gavi.jpg?itok=qdyVTfR6)
The Alternative MiP Prevention Strategies (AMPS) Study Group’s aim is to determine the safety and efficacy of novel strategies for the control of mala...
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A pooled analysis assessing the effect of mg/kg dosing strategies on the risk of treatment failure in patients treated with the currently recommended ...
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![mothers and babies](/sites/default/files/styles/research_activity_480x270/public/migrated/images/study-groups/women_children_at_health_centre_credit_rama_george-alleyne_world_bank.jpg?itok=yq8RRLd3)
The paediatric single low-dose (SLD) primaquine efficacy study group aims to assess and compare the efficacy of SLD primaquine for transmission blocki...
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![Credit Dominic Chavez, World Bank woman with child in Sierra Leone](/sites/default/files/styles/research_activity_480x270/public/2024-06/woman%20with%20child%20Sierra%20Leone%20credit%20Dominic%20Chavez%20World%20Bank.jpg?itok=ryBEKxCX)
The Study Group was formed in January 2024 to update and expand the WWARN work of the K13 Genotype-Phenotype Study Group, which was published in BMC M...
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The Dihydroartemisinin-Piperaquine for Intermittent Preventive Treatment in Pregnancy Study Group aims to determine the safety and efficacy of intermi...
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The Subpatent Malaria and Pregnancy Outcome Study Group aims to explore the relationship between subpatent Plasmodium falciparum malaria inf...
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Baseline information on parasitological response to ACTs in AsiaA pooled analysis to assess the baseline early parasitological response after artemisi...
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